History: In 1769, Morgagni gave the first clinical description of Crohn's disease in a book called “The Seats and Causes of Diseases”. "In 1865, probably the first clinical and pathological description of ulcerative colitis was recorded in the annals of the Union Army Medical Corps"(Springer.com). In 1909, Braun "described several cases of inflammatory disease masses involving the small intestine". In 1913, Dalziel reported 6 similar cases that determined that a "benign, chronic, granulomatous condition of the small intestine existed which was not tuberculosis"(Springer.com).
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Symptoms:
Quality of life:
Crohn's Disease is a "chronic, relapsing disease with an often early age of onset that can affect the entire gastrointestinal tract"(Springer.com). Crohn's Disease has a "debilitating effect on a patient’s social, educational, professional, and familial activities; thus having a profound effect on their health related quality of life"(Springer.com). The health related quality of life is a patients ability to understand and live with the impacts the disease has on their lifestyles. |
Treatments:
Involved drug therapy or in rare cases surgery. Anti-inflammatory drugs:
These reduce inflammation by targeting substances that cause inflammation.
Antibiotics can reduce the amount of drainage and sometimes heal fistulas and abscesses in people with Crohn's disease. Some researchers also think antibiotics help reduce harmful intestinal bacteria that may play a role in activating the intestinal immune system, leading to inflammation.
Surgery: this procedure is performed by removing a section of damaged digestive tract and attaching it to the healthy section. |
Diagnosis:
Blood tests:
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